The path less costly

Less costly drugs work for nausea, vomiting.

iting (PONV) at an annual cost of several hundred million dollars, preventing this common complication is a priority. A new study by Christian Apfel, MD, and his colleagues provides the first comprehensive head-to-head comparison of common treatments for preventing PONV. Their findings, published in the June 10 New England Journal of Medicine, show that drugs costing a dollar or two per dose, s...

The path(way) less traveled.

In this issue of Blood, Mathewson et al characterized targeting a novel intracellular pathway with an agent known to induce potent antitumor effects but now also appears to potently suppress inflammatory responses by dendritic cells (DCs) and prevent graft-vs-host disease (GVHD). Identifying agents that can suppress GVHD yet not compromise graft-vs-tumor (GVT) effects remains a paramount goal i...

Better and less-costly electronic voting at polling places

Meiotic Recombination: Taking the Path Less Traveled

The proper distribution of crossovers during meiosis I ensures accurate chromosome segregation at the first meiotic division. A new study reveals both the consequences of improper crossover patterning in Drosophila and the role of Blm helicase in controlling this patterning.

A LESS COSTLY CONSTBAIhTS CHECKING FUR JOIN DEPChDEKY

A set of n tuples in a relation of a relational database design is tested tlpon the constraints of the join dependency. Some constraint equalities are found to be redundant. To remove thfs superEluity, the universe of atttbutes is partitioned into n dfsjolnt sets and a new notat.ion of join dependency is introduced. The checking time In each run of n tuples is significantly reduced by a factor ...